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3100 Weslayan 3100 Weslayan St 1,129 - 20,016 sq ft of 4-Star Space Available in Houston, TX 77027

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HIGHLIGHTS

  • 3100 Weslayan offers move-in-ready medical office suites augmented by on-site conveniences such as Parks Pantry Market, security, and a day porter.
  • Highly accessible with multiple ingress and egress points, a visitor drop-off area, and a free multi-level parking garage.
  • Lush exterior features a courtyard and patio areas with an equally unique interior boasting abundant natural light and amenities.
  • Great connectivity via US 59 and Loop 610, reach The Heights, Downtown Houston, Texas Medical Center, and Sugar Land in 15 to 20 minutes.
  • Located in the heart of Greenway Plaza, close to high-end restaurants, hotels, neighborhoods, shopping, and The Galleria.
  • Medical practices are in a health-conscious area as over $166 million is spent annually on healthcare within only a 3-mile radius.

ALL AVAILABLE SPACES(9)

Display Rent as

  • SPACE
  • SIZE
  • TERM
  • RATE
  • USE
  • CONDITION
  • AVAILABLE
  • 2nd Floor, Ste 200
  • 1,343 sq ft
  • Negotiable
  • £14.59 /sq ft pa £1.22 /sq ft pcm £19,590 pa £1,632 pcm
  • Medical
  • Full Fit-Out
  • Now

Features a reception/waiting area upon entry, an open area for workstations, two private offices, and a large room connected via a sliding door.

  • Lease rate does not include utilities, property expenses or building services
  • Space is in Excellent Condition
  • Fits 4 - 11 People
  • Fully Fit-Out as Standard Medical Space
  • 2 Private Offices
  • 2nd Floor, Ste 226
  • 6,084 sq ft
  • Negotiable
  • £18.33 /sq ft pa £1.53 /sq ft pcm £111,500 pa £9,292 pcm
  • Medical
  • Shell And Core
  • Now

Open shell space ready for customization.

  • Lease rate does not include utilities, property expenses or building services
  • Space is in Excellent Condition
  • Open Floor Plan Layout
  • 2nd Floor, Ste 240
  • 1,129 sq ft
  • Negotiable
  • Upon Application Upon Application Upon Application Upon Application
  • Medical
  • Full Fit-Out
  • Now
  • Fully Fit-Out as Standard Medical Space
  • Space is in Excellent Condition
  • High-density office layout
  • 2nd Floor, Ste 250
  • 2,428 sq ft
  • Negotiable
  • £13.46 /sq ft pa £1.12 /sq ft pcm £32,692 pa £2,724 pcm
  • Office / Medical
  • Full Fit-Out
  • Now

Suite 250 opens up with a large room/waiting area with a corridor leading to back offices/exam rooms, a break room, and a conference room.

  • Lease rate does not include utilities, property expenses or building services
  • Mostly Open Floor Plan Layout
  • 1 Conference Room
  • Fully Fit-Out as Standard Office
  • Fits 7 - 20 People
  • Space is in Excellent Condition
  • 2nd Floor, Ste 253
  • 1,522 sq ft
  • Negotiable
  • £13.46 /sq ft pa £1.12 /sq ft pcm £20,493 pa £1,708 pcm
  • Office / Medical
  • Full Fit-Out
  • Now

Move-in-ready suite with a waiting room upon entry that connects via hallway to back exam rooms/office and multi-purpose rooms.

  • Lease rate does not include utilities, property expenses or building services
  • Mostly Open Floor Plan Layout
  • Space is in Excellent Condition
  • Fully Fit-Out as Standard Office
  • Fits 4 - 13 People
  • 3rd Floor, Ste 304
  • 2,992 sq ft
  • Negotiable
  • £14.59 /sq ft pa £1.22 /sq ft pcm £43,643 pa £3,637 pcm
  • Medical
  • Full Fit-Out
  • Now

Sleek space with white finishes, a welcoming reception desk, a private restroom, a break room, and several multi-purpose rooms.

  • Lease rate does not include utilities, property expenses or building services
  • Mostly Open Floor Plan Layout
  • Fully Fit-Out as Standard Medical Space
  • 3rd Floor, Ste 374
  • 1,502 sq ft
  • Negotiable
  • £13.46 /sq ft pa £1.12 /sq ft pcm £20,224 pa £1,685 pcm
  • Office / Medical
  • Full Fit-Out
  • Now
  • Lease rate does not include utilities, property expenses or building services
  • Mostly Open Floor Plan Layout
  • Space is in Excellent Condition
  • Fully Fit-Out as Standard Office
  • Fits 4 - 13 People
  • 3rd Floor, Ste 379
  • 1,593 sq ft
  • Negotiable
  • £13.46 /sq ft pa £1.12 /sq ft pcm £21,449 pa £1,787 pcm
  • Office / Medical
  • Full Fit-Out
  • Now

Spacious office-medical suite with 1,593 sqft available.

  • Lease rate does not include utilities, property expenses or building services
  • Mostly Open Floor Plan Layout
  • Space is in Excellent Condition
  • Fully Fit-Out as Standard Office
  • Fits 4 - 13 People
  • NNN - $10.50
  • 3rd Floor, Ste 380
  • 1,423 sq ft
  • Negotiable
  • £13.46 /sq ft pa £1.12 /sq ft pcm £19,160 pa £1,597 pcm
  • Office / Medical
  • Full Fit-Out
  • Now

Spacious office-medical suite with 1,423 sqft available.

  • Lease rate does not include utilities, property expenses or building services
  • Mostly Open Floor Plan Layout
  • Space is in Excellent Condition
  • Fully Fit-Out as Standard Office
  • Fits 4 - 12 People
  • NNN - $10.50
Space Size Term Rate Space Use Condition Available
2nd Floor, Ste 200 1,343 sq ft Negotiable £14.59 /sq ft pa £1.22 /sq ft pcm £19,590 pa £1,632 pcm Medical Full Fit-Out Now
2nd Floor, Ste 226 6,084 sq ft Negotiable £18.33 /sq ft pa £1.53 /sq ft pcm £111,500 pa £9,292 pcm Medical Shell And Core Now
2nd Floor, Ste 240 1,129 sq ft Negotiable Upon Application Upon Application Upon Application Upon Application Medical Full Fit-Out Now
2nd Floor, Ste 250 2,428 sq ft Negotiable £13.46 /sq ft pa £1.12 /sq ft pcm £32,692 pa £2,724 pcm Office / Medical Full Fit-Out Now
2nd Floor, Ste 253 1,522 sq ft Negotiable £13.46 /sq ft pa £1.12 /sq ft pcm £20,493 pa £1,708 pcm Office / Medical Full Fit-Out Now
3rd Floor, Ste 304 2,992 sq ft Negotiable £14.59 /sq ft pa £1.22 /sq ft pcm £43,643 pa £3,637 pcm Medical Full Fit-Out Now
3rd Floor, Ste 374 1,502 sq ft Negotiable £13.46 /sq ft pa £1.12 /sq ft pcm £20,224 pa £1,685 pcm Office / Medical Full Fit-Out Now
3rd Floor, Ste 379 1,593 sq ft Negotiable £13.46 /sq ft pa £1.12 /sq ft pcm £21,449 pa £1,787 pcm Office / Medical Full Fit-Out Now
3rd Floor, Ste 380 1,423 sq ft Negotiable £13.46 /sq ft pa £1.12 /sq ft pcm £19,160 pa £1,597 pcm Office / Medical Full Fit-Out Now

2nd Floor, Ste 200

Size
1,343 sq ft
Term
Negotiable
Rate
£14.59 /sq ft pa £1.22 /sq ft pcm £19,590 pa £1,632 pcm
Space Use
Medical
Condition
Full Fit-Out
Available
Now

2nd Floor, Ste 226

Size
6,084 sq ft
Term
Negotiable
Rate
£18.33 /sq ft pa £1.53 /sq ft pcm £111,500 pa £9,292 pcm
Space Use
Medical
Condition
Shell And Core
Available
Now

2nd Floor, Ste 240

Size
1,129 sq ft
Term
Negotiable
Rate
Upon Application Upon Application Upon Application Upon Application
Space Use
Medical
Condition
Full Fit-Out
Available
Now

2nd Floor, Ste 250

Size
2,428 sq ft
Term
Negotiable
Rate
£13.46 /sq ft pa £1.12 /sq ft pcm £32,692 pa £2,724 pcm
Space Use
Office / Medical
Condition
Full Fit-Out
Available
Now

2nd Floor, Ste 253

Size
1,522 sq ft
Term
Negotiable
Rate
£13.46 /sq ft pa £1.12 /sq ft pcm £20,493 pa £1,708 pcm
Space Use
Office / Medical
Condition
Full Fit-Out
Available
Now

3rd Floor, Ste 304

Size
2,992 sq ft
Term
Negotiable
Rate
£14.59 /sq ft pa £1.22 /sq ft pcm £43,643 pa £3,637 pcm
Space Use
Medical
Condition
Full Fit-Out
Available
Now

3rd Floor, Ste 374

Size
1,502 sq ft
Term
Negotiable
Rate
£13.46 /sq ft pa £1.12 /sq ft pcm £20,224 pa £1,685 pcm
Space Use
Office / Medical
Condition
Full Fit-Out
Available
Now

3rd Floor, Ste 379

Size
1,593 sq ft
Term
Negotiable
Rate
£13.46 /sq ft pa £1.12 /sq ft pcm £21,449 pa £1,787 pcm
Space Use
Office / Medical
Condition
Full Fit-Out
Available
Now

3rd Floor, Ste 380

Size
1,423 sq ft
Term
Negotiable
Rate
£13.46 /sq ft pa £1.12 /sq ft pcm £19,160 pa £1,597 pcm
Space Use
Office / Medical
Condition
Full Fit-Out
Available
Now

2nd Floor, Ste 200

Size 1,343 sq ft
Term Negotiable
Rate £14.59 /sq ft pa
Space Use Medical
Condition Full Fit-Out
Available Now

Features a reception/waiting area upon entry, an open area for workstations, two private offices, and a large room connected via a sliding door.

  • Lease rate does not include utilities, property expenses or building services
  • Fully Fit-Out as Standard Medical Space
  • Space is in Excellent Condition
  • 2 Private Offices
  • Fits 4 - 11 People

2nd Floor, Ste 226

Size 6,084 sq ft
Term Negotiable
Rate £18.33 /sq ft pa
Space Use Medical
Condition Shell And Core
Available Now

Open shell space ready for customization.

  • Lease rate does not include utilities, property expenses or building services
  • Open Floor Plan Layout
  • Space is in Excellent Condition

2nd Floor, Ste 240

Size 1,129 sq ft
Term Negotiable
Rate Upon Application
Space Use Medical
Condition Full Fit-Out
Available Now

  • Fully Fit-Out as Standard Medical Space
  • High-density office layout
  • Space is in Excellent Condition

2nd Floor, Ste 250

Size 2,428 sq ft
Term Negotiable
Rate £13.46 /sq ft pa
Space Use Office / Medical
Condition Full Fit-Out
Available Now

Suite 250 opens up with a large room/waiting area with a corridor leading to back offices/exam rooms, a break room, and a conference room.

  • Lease rate does not include utilities, property expenses or building services
  • Fully Fit-Out as Standard Office
  • Mostly Open Floor Plan Layout
  • Fits 7 - 20 People
  • 1 Conference Room
  • Space is in Excellent Condition

2nd Floor, Ste 253

Size 1,522 sq ft
Term Negotiable
Rate £13.46 /sq ft pa
Space Use Office / Medical
Condition Full Fit-Out
Available Now

Move-in-ready suite with a waiting room upon entry that connects via hallway to back exam rooms/office and multi-purpose rooms.

  • Lease rate does not include utilities, property expenses or building services
  • Fully Fit-Out as Standard Office
  • Mostly Open Floor Plan Layout
  • Fits 4 - 13 People
  • Space is in Excellent Condition

3rd Floor, Ste 304

Size 2,992 sq ft
Term Negotiable
Rate £14.59 /sq ft pa
Space Use Medical
Condition Full Fit-Out
Available Now

Sleek space with white finishes, a welcoming reception desk, a private restroom, a break room, and several multi-purpose rooms.

  • Lease rate does not include utilities, property expenses or building services
  • Fully Fit-Out as Standard Medical Space
  • Mostly Open Floor Plan Layout

3rd Floor, Ste 374

Size 1,502 sq ft
Term Negotiable
Rate £13.46 /sq ft pa
Space Use Office / Medical
Condition Full Fit-Out
Available Now

  • Lease rate does not include utilities, property expenses or building services
  • Fully Fit-Out as Standard Office
  • Mostly Open Floor Plan Layout
  • Fits 4 - 13 People
  • Space is in Excellent Condition

3rd Floor, Ste 379

Size 1,593 sq ft
Term Negotiable
Rate £13.46 /sq ft pa
Space Use Office / Medical
Condition Full Fit-Out
Available Now

Spacious office-medical suite with 1,593 sqft available.

  • Lease rate does not include utilities, property expenses or building services
  • Fully Fit-Out as Standard Office
  • Mostly Open Floor Plan Layout
  • Fits 4 - 13 People
  • Space is in Excellent Condition
  • NNN - $10.50

3rd Floor, Ste 380

Size 1,423 sq ft
Term Negotiable
Rate £13.46 /sq ft pa
Space Use Office / Medical
Condition Full Fit-Out
Available Now

Spacious office-medical suite with 1,423 sqft available.

  • Lease rate does not include utilities, property expenses or building services
  • Fully Fit-Out as Standard Office
  • Mostly Open Floor Plan Layout
  • Fits 4 - 12 People
  • Space is in Excellent Condition
  • NNN - $10.50

PROPERTY OVERVIEW

3100 Weslayan is a premier, four-story medical office building located in the heart of Greenway Plaza, offering an array of move-in-ready suites with free initial test fits. This property features an Energy Star rating, beautiful courtyards and patios, a day porter, on-site security with 24-hour monitored surveillance, Parks Pantry Market, and free garage parking. 3100 Weslayan’s spaces include all the medical essentials such as exam rooms, reception areas, nurse’s stations, file storage, lab space, and more. Tenants have peace of mind with professional ownership and management to curate a top-notch experience for their organization. This building has easy accessibility to several major freeways in the metroplex, including Highway 59 and Loop 610. 3100 Weslayan is also located near several high-end restaurants, hotels, and shopping, including The Galleria, Highland Village, and Rice Village. It is among a grouping of high-end neighborhoods, including River Oaks and West University Place. The building offers access to a well-educated labor pool as 71% of the population within a 3-mile radius has a bachelor’s degree or higher. The communities also provide a nearby clientele base as they tend to prioritize health and wellness. Commuters can reach Downtown Houston in about 15 minutes, and Sugar Land is 15 miles away, making this easily accessible for thousands of professionals throughout the metro.

  • 24 Hour Access
  • Controlled Access
  • Courtyard
  • Security System
  • Signage
  • Kitchen
  • Central Heating
  • Natural Light
  • Outdoor Seating
  • Air Conditioning

PROPERTY FACTS

Property Type
Office
Year Built/Renovated
1978/1993
LoopNet Rating
4 Star
Number of Floors
4
Property Size
78,745 sq ft
Costar Property Class
B
Typical Floor Size
19,686 sq ft
Clear Internal Height
11 ft
Parking
120 Surface Parking Spaces
Covered Parking

MARKETING BROCHURE

Walk Score®
Easily Walkable (88)
What is a Walk Score®, Transit Score® & Bike Score®?
Walk Score® measures how walkable a location is.
Transit Score® measures access to public transport.
Bike Score® measures how accessible a location is by bike
What is a Walk Score®
, Transit Score® & Bike Score?
Walk Score® measures how walkable
a location is. Transit Score®
measures access to public transport. Bike Score®
measures how accessible a location is by bike®

NEARBY AMENITIES

HOSPITALS

Houston Methodist Hospital Acute Care 9 min drive 4.4 mi
Memorial Hermann - Texas Medical Center Acute Care 9 min drive 4.5 mi
Texas Orthopedic Hospital Acute Care 9 min drive 4.6 mi
Shriners Hospitals for Children Children's 9 min drive 4.8 mi
Texas Childrens Hospital Children's 9 min drive 4.9 mi

RESTAURANTS

Joe's Deli Deli $ 9 min walk
Borgo Food Station Italian $ 11 min walk
Tiny Boxwoods Cafe $$$ 12 min walk
Collina's Italian Cafe Italian $$ 14 min walk
Sushi Wabi Sushi $$$$ 14 min walk
Ouisie's Table American $$ 18 min walk
Relish Restaurant & Bar Sandwiches $$ 19 min walk

RETAIL

Independent Financial Finance Company 7 min walk
Wells Fargo Bank Bank 9 min walk
Lululemon Unisex Apparel 14 min walk
Anthropologie Ladies' Apparel 14 min walk
Crate & Barrel Home Accessories 14 min walk
J.Crew Unisex Apparel 14 min walk
LA Fitness Fitness 15 min walk
Kiehl's Health & Beauty Aids 15 min walk
Sephora Health & Beauty Aids 16 min walk

HOTELS

St. Regis
232 rooms
4 min drive
Hampton by Hilton
176 rooms
5 min drive
Tapestry Collection by Hilton
284 rooms
6 min drive
La Quinta Inns & Suites
173 rooms
5 min drive
Marriott
301 rooms
5 min drive

ABOUT GREENWAY PLAZA

The focal point of Greenway is the area’s namesake 50-acre Greenway Plaza campus, which represents a third of Greenway’s office stock. After these buildings were completed in the late 1960s, developers and tenants continued to capitalize on the area’s central location between downtown and uptown Houston, its easy ingress and egress, and prime location amidst some of the strongest demographics in the country.

Median household incomes and educational levels around Greenway Plaza in the upscale River Oaks and West University residential communities compete with the upper echelon of residential neighborhoods in the United States. Houston’s cultural centers, the Museum District and Montrose neighborhood, are in close proximity to Greenway.

Rents here average in the top 10 in Houston but provide an attractive proposition for tenants who want to be located inside the Loop—with all of the best amenities—and not have to pay top-dollar rents.

LETTING AGENT

LETTING AGENT

Sandra Wolters, Senior Associate
Sandra brings 18 years of diverse experience in the real estate industry with focus on landlord agency leasing and tenant representation for the last 8 years. Sandra joined Transwestern as a senior associate on the Healthcare Advisory Team. Prior to joining Transwestern, she served as a leasing manager from Healthcare Trust of America where she was responsible for a portfolio of properties in across Texas.  At Transwestern, she focusses in working with users and owners of medical office buildings on agency leasing, tenant representation and investment services.

Since 2016, Sandra has completed over 260 lease and sale transactions and oversaw up to 2.5 million square feet representing landlords across Texas.
  • Listing ID: 21956362

  • Date on Market: 05/09/2025

  • Last Updated:

  • Address: 3100 Weslayan St, Houston, TX 77027

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